Messing around again today trying to get it working and tried turning off custom errors in the full trust web.config file - still fails but on the neatupload httpmodule - don't think it is an issue necessarily with the neatupload but seems to be the first httpmodule that it tries to load......

Should I enable debug mode in the web.config file and see if I can get any more info? 

Hi Joe,

Thanks for the input - I will describe what I did below and see if that helps make sense of anything....... (and apologies in advance for stating what is most likely obvious)

The shared hosting I use uses dotnetpanel as the control panel and I already had a couple of domains created that I just use as test domains, one of them being jrctest.......

once I have created the domain via the control panel I can connect to it via FTP and filezilla and see a number of folders under my account folder which are either the domains I host or test domains.  Under each of theses folders are 3 sub folders called data, logs and wwwroot

All I did was to upload the contents of the release files wwwroot folder into the wwwroot folder into the jrctest folder on the server so I have for example /jrcwebso/jrctest.co.uk/wwwroot/bin  

This is the way I have always done when building simpler domains and also the much more complex domain I host which runs on blogengine (although in that case I had to ask the hosting people to mark the BlogEngine folder as an ASP application......??)

Hope that this highlights some simple mistake I have made.... :-)

Thanks Joe, will give it a try and report back :-)

No problem Joe sure it will be the first of many and thanks for sharing such an amazing and complex product!

I asked them to look at permissions and they all seem fine and I am hitting the same error so assuming I need to mark mojoportal as an ASP app which folders do I need to mark (sorry for the newbie questions but blogengine.net was in a self contained folder that needed marking) as the app from the releasefiles/wwwroot folder ?

Woo Hoo - up and running! 

I had a good long chat with a guy that has been very helpful before on the Eukhost livechat and he looked into it for me.  Tried the ASP app thing but he said that was already setup correctly.  He asked me for the IIS setup instructions and once I had sent him a link to the IIS setup page on here he went off and had a root around and got it up and running in a few mins.  I asked him whether I had done something wrong or what the problem was for when I setup another site with mojoportal and was told: 

" The setup folder was setup as an application. it was not required since you were installing it on the root of the site and the wwwroot folder is already setup as an virtual application folder for your site. "

Not sure how/why the setup folder was setup as an application as its not something I have done (maybe a legacy folder from what was there before who knows.......) but the main thing is that it all works fine now and the fun can really start 

If anyone else ever wants to setup on Eukhost (under shared hosting) then it should be as simple as following Joe's instructions, using the Medium Trust setup and off you go - if you get stuck then a guy called Raymond seems very good, helpful and thorough :-)  In general I have found them to be very good and very helpful.